Yuji Naito Selected Research

Carcinogenesis

1/2019	Early-Life Microbiota Exposure Restricts Myeloid-Derived Suppressor Cell-Driven Colonic Tumorigenesis.
3/2018	Secreted protein acidic and rich in cysteine functions in colitis via IL17A regulation in mucosal CD4+ T cells.
3/2016	Protective effect of agaro-oligosaccharides on gut dysbiosis and colon tumorigenesis in high-fat diet-fed mice.
6/2013	A novel myokine, secreted protein acidic and rich in cysteine (SPARC), suppresses colon tumorigenesis via regular exercise.
1/2011	Redox biology and gastric carcinogenesis: the role of Helicobacter pylori.
12/2010	Helicobacter pylori: a ROS-inducing bacterial species in the stomach.
8/2010	Regular exercise reduces colon tumorigenesis associated with suppression of iNOS.
12/2008	Expression of inducible nitric oxide synthase and nitric oxide-modified proteins in Helicobacter pylori-associated atrophic gastric mucosa.
12/2007	Chronic oxidative stress causes amplification and overexpression of ptprz1 protein tyrosine phosphatase to activate beta-catenin pathway.
10/2006	Contrasting genome-wide distribution of 8-hydroxyguanine and acrolein-modified adenine during oxidative stress-induced renal carcinogenesis.

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Yuji Naito Research Topics

Disease

72	Inflammation (Inflammations) 01/2024 - 01/2002
53	Neoplasms (Cancer) 05/2022 - 11/2002
48	Colitis 01/2024 - 01/2002
27	Stomach Neoplasms (Stomach Cancer) 12/2023 - 01/2002
24	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 03/2023 - 01/2002
21	Ischemia 03/2022 - 01/2002
21	Hemorrhage 03/2022 - 01/2003
19	Ulcer 01/2021 - 09/2005
16	Ulcerative Colitis 01/2024 - 12/2008
14	Infections 07/2023 - 08/2002
13	Reperfusion Injury 03/2022 - 01/2002
13	Colorectal Neoplasms (Colorectal Cancer) 11/2021 - 08/2010
12	Carcinogenesis 01/2019 - 01/2002
11	Wounds and Injuries (Trauma) 01/2022 - 10/2005
10	Type 2 Diabetes Mellitus (MODY) 11/2022 - 01/2002
10	Body Weight (Weight, Body) 01/2022 - 01/2002
10	Insulin Resistance 01/2019 - 05/2004
10	Stomach Ulcer (Gastric Ulcer) 01/2018 - 09/2005
9	Dysbiosis 07/2022 - 03/2016
9	Neoplasm Metastasis (Metastasis) 01/2020 - 01/2003
9	Colonic Neoplasms (Colon Cancer) 01/2018 - 01/2003
9	Hyperthermia 07/2014 - 11/2002
8	Crohn Disease (Crohn's Disease) 12/2023 - 01/2014
8	Esophageal Neoplasms (Esophageal Cancer) 06/2022 - 08/2016
8	Gastritis 01/2022 - 08/2002
8	Non-alcoholic Fatty Liver Disease 01/2022 - 09/2010
8	Atherosclerosis 01/2019 - 05/2002
8	Hypoxia (Hypoxemia) 06/2010 - 06/2003
7	Gastrointestinal Diseases (Functional Gastrointestinal Disorders) 07/2022 - 07/2005
7	Pancreatic Neoplasms (Pancreatic Cancer) 10/2020 - 05/2009
6	Irritable Bowel Syndrome (Syndrome, Irritable Bowel) 01/2024 - 12/2017
6	Esophageal Squamous Cell Carcinoma 05/2022 - 10/2010
6	Carcinoma (Carcinomatosis) 08/2021 - 11/2002
6	Metabolic Syndrome (Dysmetabolic Syndrome X) 05/2021 - 01/2009
6	Esophagitis 01/2009 - 08/2004
5	Constipation 03/2023 - 07/2013
5	Disseminated Intravascular Coagulation 08/2021 - 06/2003
5	Enteritis 01/2019 - 01/2006
5	Polyps 06/2017 - 08/2012
5	Fibrosis (Cirrhosis) 09/2013 - 06/2010
4	Obesity 03/2022 - 03/2008
4	Adenocarcinoma 01/2022 - 02/2005

Drug/Important Bio-Agent (IBA)

34	CytokinesIBA 06/2022 - 01/2002
33	Proteins (Proteins, Gene)FDA Link 05/2022 - 01/2002
19	Messenger RNA (mRNA)IBA 01/2022 - 01/2002
16	Dextran SulfateIBA 01/2024 - 01/2002
16	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 03/2022 - 01/2002
16	Sulfonic AcidsIBA 11/2021 - 03/2006
14	Carbon MonoxideIBA 03/2022 - 04/2009
14	Peroxidase (Myeloperoxidase)IBA 05/2021 - 04/2004
13	DNA (Deoxyribonucleic Acid)IBA 04/2016 - 11/2003
12	Indomethacin (Indometacin)FDA LinkGeneric 02/2014 - 01/2006
12	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2011 - 01/2004
11	LigandsIBA 05/2019 - 01/2002
11	NF-kappa B (NF-kB)IBA 05/2009 - 01/2002
10	Biomarkers (Surrogate Marker)IBA 05/2019 - 05/2004
10	AntioxidantsIBA 12/2013 - 05/2002
9	guar gum (guaran)IBA 03/2023 - 06/2006
9	Proton Pump InhibitorsIBA 05/2022 - 01/2006
9	Thiobarbituric Acid Reactive SubstancesIBA 01/2021 - 04/2004
9	Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA 02/2014 - 03/2008
8	Heme Oxygenase-1IBA 03/2022 - 12/2008
8	Glucose (Dextrose)FDA LinkGeneric 01/2022 - 05/2007
8	Transcription Factors (Transcription Factor)IBA 01/2022 - 04/2003
8	sodium sulfate (sodium bisulfate)FDA LinkGeneric 07/2020 - 08/2004
8	Dextrans (Dextran)FDA Link 07/2020 - 08/2004
8	PPAR gammaIBA 02/2010 - 01/2002
7	Bile Acids and Salts (Bile Acids)IBA 07/2022 - 06/2011
7	Therapeutic UsesIBA 01/2021 - 08/2006
7	ZincIBA 07/2020 - 11/2002
7	Phenobarbital (Luminal)FDA Link 07/2019 - 01/2002
7	Hemoglobins (Hemoglobin)IBA 01/2017 - 05/2003
7	Vitamin E FDA LinkGeneric 09/2013 - 05/2002
7	Free RadicalsIBA 06/2012 - 04/2004
6	Fluorouracil (Carac)FDA LinkGeneric 06/2022 - 08/2012
6	Interleukin-8 (Interleukin 8)IBA 06/2022 - 01/2002
6	rebamipideIBA 07/2015 - 10/2005
5	Dietary Fiber FDA Link 03/2023 - 01/2016
5	Peptides (Polypeptides)IBA 10/2022 - 01/2013
5	Lansoprazole (Prevacid)FDA LinkGeneric 05/2022 - 10/2004
5	SolutionsIBA 01/2022 - 08/2012
5	sym-trinitrobenzeneIBA 11/2021 - 08/2013
5	AcidsIBA 08/2021 - 08/2002
5	Carotenoids (Carotene)IBA 01/2021 - 04/2008
5	polaprezinc (Z 103)IBA 04/2020 - 11/2002
5	Peroxisome Proliferator-Activated Receptors (PPAR)IBA 11/2019 - 01/2010
5	Insulin (Novolin)FDA Link 01/2019 - 05/2007
5	oxidized low density lipoproteinIBA 01/2019 - 05/2002
5	Rabeprazole (Aciphex)FDA Link 01/2017 - 09/2005
5	Chemotactic FactorsIBA 09/2012 - 04/2004
5	Pioglitazone (Actos)FDA Link 03/2011 - 01/2002
5	Nitric Oxide (Nitrogen Monoxide)FDA Link 12/2008 - 01/2002
5	Oxygen (Dioxygen)IBA 04/2007 - 04/2004
4	PrebioticsIBA 11/2023 - 05/2019

Therapy/Procedure

51	Therapeutics 11/2022 - 01/2002
19	Lasers (Laser) 01/2022 - 01/2014
18	Drug Therapy (Chemotherapy) 06/2022 - 11/2007
8	Enema (Enemas) 01/2021 - 03/2006
6	Oral Administration 10/2016 - 11/2002
5	Blood Vessel Prosthesis 01/2018 - 12/2011